Reaction of tertiary formamides with sulphur tetrafluoride. Direct synthesis of (trifluoromethyl) amines

W Dmowski, M Kamiński

Index: Dmowski, Wojciech; Kaminski, Maciej Journal of Fluorine Chemistry, 1983 , vol. 23, p. 207 - 218

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Citation Number: 35

Abstract

Abstract Treatment of dimethylformamide 1a, diethylformamide 1b, 1-formylpiperidine 3a, 4- formylmorpholine 3b, and ethyl-phenylformamide 5 with sulphur tetrafluoride in the presence of potassium fluoride resulted in a direct conversion of the formyl group to the trifluoromethyl group to give excellent yields of dimethyl (trifluoromethyl) amine 2a, diethyl (trifluoromethyl) amine2b, 1-(trifluoromethyl) piperidine 4a, 4-(trifluoromethyl) morpholine ...