Novel (3, 5-di-tert-butyl-2-hydroxy-phenylcarbamoyl)-alkanoic acids as potent antioxidants

VI Lodyato, IL Yurkova, VL Sorokin, OI Shadyro…

Index: Lodyato, Vladimir I.; Yurkova, Irina L.; Sorokin, Viktor L.; Shadyro, Oleg I.; Dolgopalets, Vladimir I.; Kisel, Mikhail A. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 16 p. 4253 - 4256

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Citation Number: 8

Abstract

A series of novel phenolic antioxidants of amphiphilic structure has been synthesized. Investigations into the influence of aliphatic spacer length and nature of a hydrophilic anchor on the antioxidant activity allowed elucidating certain structure requirements for the membrane-addressed antioxidant designing.