Die Struktur des Bisindolalkaloides Amatain (= Grandifolin, Subsessilin)

VC Agwada, J Naranjo, M Hesse…

Index: Agwada; Naranjo; Hesse; et al. Helvetica Chimica Acta, 1977 , vol. 60, # 8 p. 2830 - 2853

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Citation Number: 6

Abstract

Summary Amataine (1) was isolated from the roots of Hedranthera barteri (HOOK. F.) PICHON (Apocynaceae). In comparison to the alkaloid vobtusine (5), which was isolated from the same plant, 1 contains two hydrogen atoms less. By reduction of 1 with H2/Pt02 or with NaBH4 dihydroamataine (= isovobtusine, 13) was formed which is isomeric to 5. Acid catalysed water addition to 1 afforded hydratoamataine (15), which was reduced to 5 with ...