Regioselective hydride reduction of 2-(N-cyanoimino) thiazolidine derivatives

…, M Fujimoto, M Watanabe, T Kawakami, N Maeda…

Index: Iwata, Chuzo; Fujimoto, Michitaro; Watanabe, Mayumi; Kawakami, Tetsuya; Maeda, Noriko; et al. Heterocycles, 1991 , vol. 32, # 12 p. 2471 - 2478

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Abstract

Résumé/Abstract Treatment of 3-alkyl-2-(N-cyanoimino) thiazolidines with lithium aluminium hydride caused reductive cleavage of the imino double bond to afford 3-alkylthiazolidines, while diisobutylaluminium hydride reduction of 3-alkyl-and 3-sulfonyl derivatives resulted in the nitrile reduction or imino-nitrile bond cleavage to give 2-formyliminothiazolidines and/or 2-iminothiazolidines.