Synlett

Synthesis of Quinazolines and Imidazo [1, 2-c] quinazolines with the Aid of a Low-Valent Titanium Reagent

D Shi, J Wang, C Shi, L Rong, Q Zhuang, H Hu

Index: Shi, Daqing; Wang, Juxian; Shi, Chunling; Rong, Liangce; Zhuang, Qiya; Hu, Hongwen Synlett, 2004 , # 6 p. 1098 - 1100

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Citation Number: 18

Abstract

Abstract A short and facile synthesis of a series of quinazolines and imidazo [1, 2-c] quinazolines was accomplished in good yields via the novel reductive cyclization of 2- nitrobenzyl amines or 2-(2-nitrophenyl) imidazoles with ortho-ester, aldehydes or ketones promoted by TiCl 4/Zn system. The structures were established by spectroscopic data and confirmed by X-ray analysis.

An efficient synthesis of quinazoline derivatives with the aid of low??valent titanium reagent

[Shi, Daqing; Shi, Chunling; Wang, Juxian; Rong, Liangce; Zhuang, Qiya; Wang, Xiangshan Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 2 p. 173 - 183]

Imidazo [1, 2-c] quinazolines with lipid peroxidation inhibitory effect

[Domany, Gyoergy; Gizur, Tibor; Gere, Aniko; Takacs-Novak, Krisztina; Farsang, Gyoergy; Ferenczy, Gyoergy G.; Tarkanyi, Gabor; Demeter, Maria European Journal of Medicinal Chemistry, 1998 , vol. 33, # 3 p. 181 - 187]

Imidazo [1, 2-c] quinazolines with lipid peroxidation inhibitory effect

Synthesis of Quinazolines and Imidazo [1, 2-c] quinazolines with the Aid of a Low-Valent Titanium Reagent

Abstract

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