RSC Advances

Efficient microwave-assisted preparation of squaric acid monoamides in water

C López, M Vega, E Sanna, C Rotger, A Costa

Index: Lopez, Carlos; Vega, Manuel; Sanna, Elena; Rotger, Carmen; Costa, Antoni RSC Advances, 2013 , vol. 3, # 20 p. 7249 - 7253

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Citation Number: 5

Abstract

Squaric acid monoamides (SQAMs) were prepared via microwave-enhanced direct reaction of amines with squaric acid in yields ranging from 41 to 92%. These compounds are strong acids, with pKa values ranging from 0.9 to 2.0 as determined by spectrophotometric titration in representative cases.