Synthesis and antibacterial activity of substituted flavones, 4-thioflavones and 4-iminoflavones

…, M Ayaz, Z Hussain, A Hasan, A Sadiq, M Riaz…

Index: Ullah Mughal, Ehsan; Ayaz, Muhammad; Hussain, Zakir; Hasan, Aurangzeb; Sadiq, Amina; Riaz, Muhammad; Malik, Abdul; Hussain, Samreen; Choudhary, M. Iqbal Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 14 p. 4704 - 4711

Full Text: HTML

Citation Number: 36

Abstract

Synthesis of flavones, 4-thioflavones and 4-iminoflavones was carried out with the substitution of variable halogens, methyl, methoxy and nitro groups in the A, B and AB rings of the respective compounds and we also report here their antibacterial activity. Most of the synthesized compounds were found to be active against Escherichia coli, Bacillus subtilis, Shigella flexnari, Salmonella aureus, Salmonella typhi and Pseudomonas aeruginosa. ...

Related Articles:

Sodium selenite-dimethylsulfoxide: a highly efficient reagent for dehydrogenation

[Lamba, Mandeep; Makrandi, Jagdish Kumar Journal of Chemical Research, 2008 , # 4 p. 225 - 226]

Synthesis of Flavones and γ??Benzopyranones Using Mild Sonogashira Coupling and 18??Crown??6 Ether Mediated 6??endo Cyclization

[Chuang, Da-Wei; El-Shazly, Mohamed; Balaji D., Barve; Chung, Yu-Ming; Chang, Fang-Rong; Wu, Yang-Chang European Journal of Organic Chemistry, 2012 , # 24 p. 4533 - 4540,8]

Methoxyflavone inhibitors of cytochrome P450

[McKendall, Michael; Smith, Tasha; Anh, Kien; Ellis, Jamie; McGee, Terri; Foroozesh, Maryam; Zhu, Naijue; Stevens, Cheryl L. Klein Journal of Chemical Crystallography, 2008 , vol. 38, # 4 p. 231 - 237]

Palladium (II)-Catalyzed Oxidative Arylation of Quinoxalin-2 (1 H)-ones with Arylboronic Acids

[Kim, Donghee; Ham, Kyungrok; Hong, Sungwoo Organic and Biomolecular Chemistry, 2012 , vol. 10, # 36 p. 7305 - 7312]

Oxythallation of flavenes. I; direct conversion of flavenes to flavones with thallium (III) nitrate.

[Hatam, N. A. R.; Nacy, W. G. Tetrahedron Letters, 1983 , vol. 24, # 41 p. 4455 - 4456]

More Articles...