A new easy method for the synthesis of cyclic halogenoethers and halogenolactones

M Srebnik, R Mechoulam

Index: Srebnik, Morris; Mechoulam, Raphael Journal of the Chemical Society, Chemical Communications, 1984 , # 16 p. 1070 - 1071

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Citation Number: 14

Abstract

Oxidation of halogen salts with m-chloroperbenzoic acid in the presence of 18-crown-6 and of suitable hydroxy or carboxy alkenes leads readily to high yield production of cyclic halogenoethers or halogenolactones. ... Cyclic halogenoethers and halogenolactones are of consider- able inherent interest and synthetic utility.1.2 We report a new route to these types of compounds, which is preparatively ... X = Br (91'/0) x = c1(55%) (75 '/o ) x = I(70%)