Synthesis

Tertiary 3-aminopropenones and 3-aminopropenoates: their preparation, with and without Lewis acids, from secondary amines and 1, 3-diketo compounds

RK Vohra, JL Renaud, C Bruneau

Index: Vohra, Ramandeep Kaur; Renaud, Jean-Luc; Bruneau, Christian Synthesis, 2007 , # 5 p. 731 - 738

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Citation Number: 10

Abstract

Abstract A direct method for the preparation of tertiary 3-aminopropenones and 3- aminopropenoates from β-diketones and β-keto esters, and secondary amines has been developed. The reaction is performed without solvent in the presence or absence of Lewis acid as catalyst, depending on the reactivity of both the amine and the diketo substrate.