Highly efficient ruthenium (II) porphyrin catalyzed amidation of aldehydes

JWW Chang, PWH Chan

Index: Chang, Joyce Wei Wei; Chan, Philip Wai Hong Angewandte Chemie - International Edition, 2008 , vol. 47, # 6 p. 1138 - 1140

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Citation Number: 121

Abstract

The installation of the amide bond functionality is of immense interest in organic synthesis owing to the prevalence of this structural motif in a myriad of compounds of biological, pharmaceutical, and materials interest.[1] Conventional routes to this ubiquitous class of nitrogen-containing compounds have relied heavily upon the coupling of activated carboxylic acid and amine precursors.[2] Although these methodologies have been shown ...