An Approach to the Synthesis of Bakkenolide A

SF Campbell, MG Constantino…

Index: Campbell,S.F. et al. Synthetic Communications, 1975 , vol. 5, # 5 p. 353 - 358

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Citation Number: 6

Abstract

Abstract Bakkenolide A 1 is the simplest member of a new class of eremophilane sesquiterpenes isolated a few years ago from Petasites japonicus. 2 A recent synthesis of 1 3 prompts us to disclose our preliminary results which, in a model system, provide an alternative approach to the construction of the novel β-methylene-γ-spirolactone system present in the bakkenolide series.

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