Mono-and Difunctional Analogs of Some Quinoline and Acridine Nitrogen Mustards1

RM PECK, RK PRESTON…

Index: Peck,R. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 3409 - 3414

Full Text: HTML

Citation Number: 25

Abstract

7L'hch pronounced antitumor activity displayed by two eth~ l-2-chloroethylai: iirio: tl~ yla~ iiino derivativte of acridine led to t II (: s\ mthrsis of fiftwn quinoline and acridine analogs of this type for studies of their structrire-activit!. relationships com-I):, irwl\ vit ti t hoscl of th (1 correspoiiding bis (2-chloroethyl) forms. Sisteen other alkylating agents which incorI) or: ttcid a vxripty I,] iiiot1itic: itioiis both iii the si&>(S1i: iin: ind in the qiiinoline or avridine uiirlcws ...

Related Articles:

Synthesis and DNA-sequence selectivity of a series of mono-and difunctional 9-aminoacridine nitrogen mustards

[Kohn, Kurt W.; Orr, Ann; O'Connor, Patrick M.; Guziec, Lynn James; Guziec, Frank S. Journal of Medicinal Chemistry, 1994 , vol. 37, # 1 p. 67 - 72]

The Preparation of Some 1-Alkylamino-and Dialkylaminoalkylaminothiaxanthones1

[Archer; Suter Journal of the American Chemical Society, 1952 , vol. 74, p. 4296,4301]

More Articles...