Tetrahedron

A synthetic approach to 1, 3, 4-thiadiazolidine-2-thiones

FC Heugebaert, JF Willems

Index: Heugebaert,F.C.; Willems,J.F. Tetrahedron, 1966 , vol. 22, p. 913 - 923

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Citation Number: 10

Abstract

The course of the reaction between dithiocarbazic acid and aldehydes and ketones has been examined. Aliphatic and π-deficient heterocyclic aldehydes and ketones form 1, 3, 4- thiadiazolidine-2-thiones. Aromatic and π-excessive heterocyclic aldehydes and ketones, however, form azines. A similar course occurs in the reaction between the hydrazones and carbon disulphide. Alkyl dithiocarbazic acids (azine formation being excluded) form 3- ...