Synthesis

A fresh air synthesis

MJ Humphries, CA Ramsden

Index: Humphries, Mark J.; Ramsden, Christopher A. Synthesis, 1999 , # 6 p. 985 - 992

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Citation Number: 13

Abstract

Abstract: Two short synthetic routes to the biosynthetic purine precursor 5-aminoimidazole ribonucleotide (AIR) based on catalytic reduction of 5-nitroimidazoles are described. The synthetic ribonucleoside AIRs, which is also available via one of these routes, is a convenient intermediate for the synthesis of nucleoside analogues and preparations of the novel" pyridine-stretched" analogues of adenosine and inosine are described. Key words: ...