Stereochemistry of trityl compounds. V. Resolution of phenylbiphenylyl-. alpha.-naphthylcarbinol

BL Murr, C Santiago, S Wang

Index: Murr,B.L. et al. Journal of the American Chemical Society, 1969 , vol. 91, # 14 p. 3827 - 3831

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Citation Number: 3

Abstract

Abstract: A new method has been developed for the resolution of (+)-and (-)- phenylbiphenylyl-a-naphthylcar-binol. The alcohols had been partially resolved by Wallis.*(= t)-Ar3COH was converted to (= t)-Ar3COCH2-C02H by alkylation of ethyl glycolate with Ar3CCl followed by saponification.(-)-Ar3COCH2C02H was separated as the brucine salt and (+)-Ar3COCH2C02H was separated as the cinchonidine salt. Each enantiomeric ...