Synthesis of t-butyldimethylsilyl enol ethers from sterically hindered ketones

LN Mander, SP Sethi

Index: Mander, Lewis N.; Sethi, S. Paul Tetrahedron Letters, 1984 , vol. 25, # 51 p. 5953 - 5956

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Citation Number: 72

Abstract

... SYNTHESIS 0F tUTYLDIMETHYLSILYL ENOL ETHERS FROM STERICALLY HINDERED K ETON ES Lewis N. Mander and S ... Scheme 2. O 4-f- 5m~n 00% n 1,2,3 O o~H- 0~i I, ~ 2 {~j + [~~J 5 min 00% 64 3e o 3 CH,CH2-~CH2---CH, CH,HCH,H, 5 min 00% E+Z 7 83 4 ~0 ~ 5mm 00% 5 ~O ~ 5mm 100% 6 ~~~Ac ~ 30mm 5% ~ MeO~T~r Me0~~~5mm 8% 5955 ENTRY SUBSTRATE PRODUCT TIME YIELD , tsm-+ Ac0~~~ I HO~ CH~ A~O~ MOMO~ HnC,p H ...