Synthesis of 1H-2, 3-dihydropyrrolizine derivatives as precursors of bifunctional alkylating agents
S Rajaraman, LS Jimenez
Index: Rajaraman, Shanthi; Jimenez, Leslie S. Tetrahedron, 2002 , vol. 58, # 52 p. 10407 - 10412
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Citation Number: 12
Abstract
Two 1H-2, 3-dihydropyrrolizine derivatives bearing a nitro group at the 6 position have been synthesized and an improved method for nitrating pyrroles using potassium nitrate in trifluoroacetic acid was developed. An efficient, two-step synthesis of the butterfly pheromone, Danaidone, was also developed with an overall 33% yield.
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