Synthesis and antibacterial activity of new derivatives of 1, 4-di-N-oxides of quinoxaline

…, EV Adamskaya, SA Aleinikova, TP Radkevich…

Index: Glushkov, R. G.; Vozyakova, T. I.; Adamskaya, E. V.; Aleinikova, S. A.; Radkevich, T. P.; et al. Pharmaceutical Chemistry Journal, 1994 , vol. 28, # 1 p. 17 - 20 Khimiko-Farmatsevticheskii Zhurnal, 1994 , vol. 28, # 1 p. 15 - 17

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Citation Number: 2

Abstract

In the series of derivatives of 1, 4-di-N-oxides of quinoxaline, compounds are known which exhibit high antibacterial activity: the drugs quinoxaline and dioxidine, and also analogs containing fluorine and chlorine atoms in the 6 position [1-3]. With the goal of searching for new drugs with a broad spectrum of antibacterial action, it was of interest to synthesize and study the biological activity of compounds containing chlorine or fluorine atoms in the 6 ...