Development of immunoassays for type II synthetic pyrethroids. 1. Hapten design and application to heterologous and homologous assays

N Lee, DP McAdam, JH Skerritt

Index: Lee, Nanju; McAdam, David P.; Skerritt, John H. Journal of Agricultural and Food Chemistry, 1998 , vol. 46, # 2 p. 520 - 534

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Citation Number: 78

Abstract

Immunoassays differing in selectivities for pyrethroid insecticides have been developed for the detection of type II pyrethroids, including deltamethrin, cypermethrin, and λ-cyhalothrin. Two approaches were employed in hapten synthesis to raise antibodies with different cross- reactions:(1) use of three spacer attachment points to offset different parts of molecules from the points of attachment and (2) use of linkers with and without bulky groups in the ...