Tetrahedron Letters

Cascade Wittig reaction-double Claisen and Cope rearrangements: one-pot synthesis of diprenylated coumarins gravelliferone, balsamiferone, and 6, 8- …

RE Patre, JB Shet, PS Parameswaran, SG Tilve

Index: Patre, Rupesh E.; Shet, Jyoti B.; Parameswaran, Perunninakulath S.; Tilve, Santosh G. Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6488 - 6490

Full Text: HTML

Citation Number: 11

Abstract

Cascade, 1 domino 2 or tandem 3 reactions play an important role in the construction of complex molecular framework in fewer steps leading to saving time, cost, and energy. In 2002, Schobert and Gordon reviewed domino Wittig and pericyclic reactions for bioactive heterocycles. 4a Taylor and Quesada reported a tandem Horner–Wadsworth–Emmons olefination/Claisen rearrangement/hydrolysis sequence. 4b In continuation of our interest in such reactions, ...