Design of 3-(4-carboxybenzoyl)-2-quinolinecarboxaldehyde as a reagent for ultrasensitive determination of primary amines by capillary electrophoresis using laser …

J Liu, YZ Hsieh, D Wiesler, M Novotny

Index: Liu, Jinping; Hsieh, You-Zoung; Wiesler, Donald; Novotny, Milos Analytical Chemistry, 1991 , vol. 63, # 5 p. 408 - 412

Full Text: HTML

Citation Number: 210

Abstract

Amino acids and peptides, from both standard solutions and biological samples, were successfully reacted with 34 4-carboxybenroyi)-2-quinoiinecarboxaidehyde, at low concentration, to form highly fluorescent isoindole derivatives. The formed mixtures are effectively separated by high-performance capillary electrophoresis and their constituents detected by their laser-induced fluorescence signals. The minimum detectable quantities ...