Sterically hindered esters of vitamin A II: Vitamin A α, α??dimethylpalmitate

AJ Forlano, CI Jarowski, HF Hammer…

Index: Forlano; Jarowski; Hammer; Merritt Journal of pharmaceutical sciences, 1970 , vol. 59, # 1 p. 121 - 123

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Citation Number: 4

Abstract

Abstract A previous study showed that short-chain sterically hindered esters of vitamin A demonstrated better stability in solution than the commercial plamitate. The oxidative stability of the short-chain sterically hindered esters, however, was poor. This work indicated that a long aliphatic chain with steric hindrance in the α-position was necessary for maximal stability. A compound of this type, vitamin A α, α-dimethylpalmitate, was prepared and ...