Tetrahedron Letters

Bioluminescence activity of Latia luciferin analogs

S Kojima, S Maki, T Hirano, Y Ohmiya, H Niwa

Index: Kojima, Satoshi; Maki, Shojiro; Hirano, Takashi; Ohmiya, Yoshihiro; Niwa, Haruki Tetrahedron Letters, 2000 , vol. 41, # 22 p. 4409 - 4413

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Citation Number: 13

Abstract

Latia luciferin analogs were synthesized and their bioluminescence activities were measured. The Latia luciferase was found to recognize strictly the 2, 6, 6- trimethylcyclohexene ring moiety in the luciferin structure. While the enol ether analogs exhibited no bioluminescence activity, the corresponding enol acetate analog possessed 60% activity compared to natural luciferin having an enol formate structure, implying that ...

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