Coumarin-4-ylmethoxycarbonyls as phototriggers for alcohols and phenols

…, M Kawamoto, K Nishiyama, H Yamashita, M Ishii…

Index: Suzuki, Akinobu Z.; Watanabe, Takayoshi; Kawamoto, Mika; Nishiyama, Keiko; Yamashita, Hirotaka; Ishii, Megumi; Iwamura, Michiko; Furuta, Toshiaki Organic Letters, 2003 , vol. 5, # 25 p. 4867 - 4870

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Citation Number: 119

Abstract

Caged compounds can be used to regulate the spatial and temporal dynamics of signaling molecules in live cells. Photochemical properties of coumarin-4-ylmethoxy carbonates (1a- d) are investigated to construct caged compounds of hydroxy-containing molecules. All the compounds possess desired properties as phototriggers for alcohols and phenols. The 6- bromo-7-hydroxycoumarin-4-ylmethoxycarbonyl (Bhcmoc) group has the highest ...