Formamidines with antinociceptive and antiinflammatory activities

…, G Boatto, A Pau, F Sparatore, L Cima, M Carrara…

Index: Cerri; Boatto; Pau; Sparatore; Cima; Carrara; Satta Farmaco, 1991 , vol. 46, # 2 p. 369 - 378

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Citation Number: 5

Abstract

Pursuing our investigations on 7-amino-2, 3-polymethyleneindole derivatives, a set of 7-( dimethylaminomethylene)-amino-2, 3-polymethyleneindoles, together with some other aryl or cycloalkyl substituted formamidines, were prepared and tested for analgesic and antiinflammatory activities. Several compounds resulted endowed with one or both of these activities; the indole derivatives 1 and 2 exhibited a good degree of both of them.