Advanced Synthesis & Catalysis

Examination of the aromatic amination catalyzed by palladium on charcoal

A Komáromi, Z Novák

Index: Komaromi, Anna; Novak, Zoltan Advanced Synthesis and Catalysis, 2010 , vol. 352, # 9 p. 1523 - 1532

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Citation Number: 12

Abstract

Abstract The Buchwald–Hartwig amination of aryl halides with secondary amines and functionalized aromatic amines catalyzed by solid-supported palladium is reported. The choices of ligand, base and solvent are crucial for the successful coupling. The amination of aromatic iodides, bromides and chlorides can be easily achieved with palladium on charcoal in the presence of a biphenylphosphane-type ligand at 80–110 C. In addition, ...

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