Oxidative methoxycarbonylation of propyne and allene with carbon monoxide and methanol in the presence of copper-palladium catalyst

AG Mal'kina, RN Kudyakova, VV Nosyreva…

Index: Mal'kina; Kudyakova; Nosyreva; Afonin; Trofimov Russian Journal of Organic Chemistry, 2002 , vol. 38, # 8 p. 1088 - 1092

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Citation Number: 6

Abstract

Abstract A direct oxidative methoxycarbonylation of propyne with carbon monoxide in methanol medium in the presence of copper-palladium catalytic system results in methyl 2- butynoate in 18-31% yield. Depending on reaction conditions allene provides either a mixture of methyl 2-(chloromethyl) acrylate and methyl 2-(methoxymethyl) acrylate (∼ 3-4: 1) in overall yield 16-23%, or methyl 2-(methoxymethyl) acrylate in 19% yield.