Chemoinformatic analysis of a supertargeted combinatorial library of styryl molecules

…, J Brumer, YT Chang, GR Rosania

Index: Rosania, Gustavo R.; Lee, Jae Wook; Ding, Liang; Yoon, Hai-Shin; Chang, Young-Tae Journal of the American Chemical Society, 2003 , vol. 125, # 5 p. 1130 - 1131

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Citation Number: 28

Abstract

Styryl dyes are fluorescent, lipophilic cations that have been used as specific labeling probes of mitochondria in living cells. For specific applications such as epifluorescence microscopy or flow cytometry, it is often desirable to synthesize fluorescent derivatives with optimized excitation, emission, and localization properties. Here, we present a chemoinformatic strategy suitable for multiparameter analysis of a combinatorial library of ...