Quinazolines and 1, 4-Benzodiazepines. X. 1 Nitro-Substituted 5-Phenyl-1, 4-benzodiazepine Derivatives2

LH Sternbach, RI Fryer, O Keller…

Index: Sternbach,L.H. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 261 - 265

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Citation Number: 79

Abstract

Results In the various tests for antagonism to reserpine and potentiation of adrenergic agents, the dimethylaminopropyl derivative of each ring system showed optimum activity and was taken as the representative member. A comparison of the effective doses of the dimethylaminopropyl derivatives of four ring systems with those of imipramine (I) is given in Table 111.