Tetrahedron letters

Sodium borohydride-amberlyst-15 (H+): An effective reductor for hindered and unreactive ketones in aprotic solvent

JR Caycho, FG Tellado, P de Armas, J Juan…

Index: Caycho, Juana Robles; Tellado, Fernando Garcia; De Armas, Pedro; Tellado, Jose Juan Marrero Tetrahedron Letters, 1997 , vol. 38, # 2 p. 277 - 280

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Citation Number: 16

Abstract

The combination of sodium borohydride and amberlyst-15 (H+) in tetrahydrofurane is a powerful reductor for unreactive ketones. The reduction is fast, high-yielding and the work- up is extremely simple. Ketals, silyl ethers and other organic functions are not disturbed during the reduction.

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