An Improved Stereoselective Synthesis of L??Alanosine

P Strazzolini, MG Dall'Arche, M Zossi…

Index: Strazzolini, Paolo; Dall'Arche, Maria Grazia; Zossi, Maura; Pavsler, Andrea European Journal of Organic Chemistry, 2004 ,  # 22  p. 4710 - 4716

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Citation Number: 7

Abstract

Abstract An improved, stereoselective synthesis of the natural, non-proteogenic amino acid L-alanosine has been developed, starting from the readily available and cheap substrate L- serine, in six steps and 49% overall yield. The process is very efficient, is suitable for large- scale production, and affords L-alanosine with properties comparable with those of the natural substance. In addition, the structural assignment concerning some previously ...