Synthesis of optically active. beta.,. gamma.-epoxy alcohols and secondary allylic alcohols via diastereoselective addition of. alpha.-(trimethylsilyl)-. alpha.,. beta.- …

Y Takeda, T Matsumoto, F Sato

Index: Takeda, Yoshiyuki; Matsumoto, Takashi; Sato, Fumie Journal of Organic Chemistry, 1986 ,  vol. 51,  # 24  p. 4728 - 4731

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Citation Number: 43

Abstract

" The reactions were carried out at-78-0'C (1-2 h) in ether.* Determined by HPLC analysis. cErythro isomers were assigned by spectroscopic methods and by comparison with the authentic materials. Isolated yields. e Purified by column chromatography on silica gel./The ratio was lowered to 2.8: 1 by using THF as solvent. gThe ratio was lowered to 2.6: l in THF.