Convergent stereocontrolled synthesis of 13-hydroxy-9 Z, 11 E-octadecadienoic acid (13-HODE)

C Chan, PB Cox, SM Roberts

Index: Chan, Cecil; Cox, Philip B.; Roberts, Stanley M. Journal of the Chemical Society, Chemical Communications, 1988 ,  # 14  p. 971 - 972

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Citation Number: 14

Abstract

Convergent Stereocontrolled Synthesis of 13-Hydroxy-SZ,I 1 E-octadecadienoic Acid (1 3-HODE) ... Cecil Chan, Philip B. Cox, and Stanley M. Roberts Department of Chemistry, University of Exeter, Exeter, Devon EX4 4QD, UK ... The readily available alkenes (4) and (5) were coupled using a palladium(ii) catalyst to give the diene ester (6), a late-stage intermediate to 13-HODE. ... HODE) (la) has been isolated from the seed oil of Coriaria Nepalensisl ; the ...