Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl-and N-methylpyrrole

RE Bremer, JW Szewczyk, EE Baird…

Index: Bioorganic and Medicinal Chemistry, , vol. 8, # 8 p. 1947 - 1955

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Citation Number: 39

Abstract

... Bioorganic & Medicinal Chemistry. ... Introduction. Cell-permeable small molecules with the ability to target predetermined DNA sequences and interfere with gene expression would be valuable tools in molecular biology and potentially in human medicine. ...