Synthesis, biological activity, and three-dimensional quantitative structure-activity relationship model for a series of benzo [c] quinolizin-3-ones, nonsteroidal inhibitors …

EG Occhiato, A Ferrali, G Menchi…

Index: Journal of Medicinal Chemistry, , vol. 47, # 14 p. 3546 - 3560

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Citation Number: 30

Abstract

... Journal of Medicinal Chemistry. ... control of the biological action of steroids through the inhibition of specific enzymes involved in their metabolism, without significant changes in the overall profile of the other hormones, has represented an attractive pharmaceutical target during ...

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