An efficient regioselective NBS aromatic bromination in the presence of an ionic liquid

SRK Pingali, M Madhav, BS Jursic

Index: Pingali, Subramanya R.K.; Madhav, Monika; Jursic, Branko S. Tetrahedron Letters, 2010 , vol. 51, # 10 p. 1383 - 1385

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Citation Number: 26

Abstract

A simple, efficient, and rapid method was developed for high-yielding regioselective monobromination of activated aromatic compounds using NBS in combination with ionic liquid 1-butyl-1-methylimidazolium bromide ([Bmim] Br) or dioxane. The ionic liquid is recyclable and can be reused with minimal loss in the catalytic efficiency if the ionic liquid is rapidly microwaved prior to reactions.