Novel Traceless Liquid??Phase Synthesis of Coumarin Derivatives on Poly (Ethylene Glycol) Support

SR Sheng, PG Huang, Q Wang, R Huang…

Index: Sheng, Shou-Ri; Huang, Pei-Gang; Wang, Qiong; Huang, Ren; Liu, Xiao-Ling Synthetic Communications, 2006 , vol. 36, # 21 p. 3175 - 3181

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Abstract

Abstract Coumarin derivatives were prepared by the von Pechmann reaction of PEG??bound acetoacetate reagent with phenols in the presence of TiCl4 in excellent yield and purity with a facile workup procedure. The polymer reagent could be recycled two to four times without diminishing the yield or purity.

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