Organic letters

Gold (III)-mediated aldol condensations provide efficient access to nitrogen heterocycles

H Waldmann, GV Karunakar, K Kumar

Index: Waldmann, Herbert; Karunakar, Galla V.; Kumar, Kamal Organic Letters, 2008 , vol. 10, # 11 p. 2159 - 2162

Full Text: HTML

Citation Number: 48

Abstract

Polycyclic N-heterocycles form the basic frameworks of numerous natural product classes and hold a prominent role in pharmaceutical and agrochemical research.(1) In particular, quinolines and their derivatives often are endowed with biological activity including compounds with antitumor activity,(2) CysLT (LTD4) receptor antagonists(3) and HIV-1 replication inhibitors.(4) For quinoline synthesis, the Friedländer annulation(5) is widely used. It proceeds both in the presence ...

Related Articles:

1, 5-Diketone synthesis promoted by barium hydride or barium alkoxides

[Takahashi, Hiroshi; Arai, Takayoshi; Yanagisawa, Akira Synlett, 2006 , # 17 p. 2833 - 2835]

Aluminum Bis (trifluoromethylsulfonyl) amides: New Highly Efficient and Remarkably Versatile Catalysts for CC Bond Formation Reactions

[Marx, Andreas; Yamamoto, Hisashi Angewandte Chemie - International Edition, 2000 , vol. 39, # 1 p. 178 - 181]

SmI3 mediated reginospecific Michael addition of ω-bromo-acetophenone to α, β-unsaturated alkynones

[Zheng, Xingliang; Zhang, Yongmin Journal of Chemical Research, 2004 , # 6 p. 412 - 413]

1, 5-Diketone synthesis promoted by barium hydride or barium alkoxides

[Takahashi, Hiroshi; Arai, Takayoshi; Yanagisawa, Akira Synlett, 2006 , # 17 p. 2833 - 2835]

Alkali metal hydride or aqueous hydroxide induced conjugate addition of trimethylsilyl enol ethers to enones. A convenient alternative to Lewis acid mediated reaction

[Swamy, Vishwanath M.; Sarkar, Amitabha Tetrahedron Letters, 1998 , vol. 39, # 10 p. 1261 - 1264]

More Articles...