New zirconocene-coupling route to large, functionalized macrocycles

JR Nitschke, S Zürcher, TD Tilley

Index: Nitschke, Jonathan R.; Zuercher, Stefan; Don Tilley Journal of the American Chemical Society, 2000 , vol. 122, # 42 p. 10345 - 10345

Full Text: HTML

Citation Number: 77

Abstract

The development of a new macrocyclization reagent, Rosenthal's Cp2Zr (pyr)(Me3SiC⋮ CSiMe3), has allowed the preparation of two large, functionalized macrocycles. The diyne 5, 5'-bis (4-trimethylsilylphenyl)-2, 2'-bipyridine was trimerized to the bipyridine-containing macrocycle 5, and 1, 4-bis (4-(trimethylsilyl) ethynyl-phenyl)-2, 3-diphenyl-1, 4-diazabuta-1, 3-diene was dimerized to macrocycle 6. Both zirconocene-containing macrocycles were ...