Synthesis of phenothiazines. III. Derivatives of hydroxy-and mercaptophenothiazines1

EA NODIFF, S LIPSCHUTZ, PN CRAIG…

Index: Nodiff,E.A. et al. Journal of Organic Chemistry, 1960 , vol. 25, p. 60 - 65

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Citation Number: 80

Abstract

The early French work in the phenothiazine field, following the lead of chloropromazine, resulted in the synthesis of the 2-methyl and 2-methoxy derivative^.^ Further work in France5 and in Switzerland, 6 as well as independent work in our laboratories, produced the 2-methylmercapto-and 2-methylsulfonyl-phenothiazines. The development of the potent l0- aminoalkyl-2-trifluoromethylphe-

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