Synthesis of halogenated phenols by directed ortho-lithiation and ipso-iododesilylation reactions of O-aryl N-isopropylcarbamates

M Kauch, D Hoppe

Index: Synthesis, , # 10 p. 1578 - 1589

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Citation Number: 14

Abstract

... Herein, we demonstrate the usefulness of this strategy to synthesize o-iodo- and o,o′-diiodophenols. ... Scheme 3 Synthesis of o-iodoaryl carbamates 17. ... [16] Consequently, the O-acetyl and O-TBS protected alcohols 18 were synthesized and subjected to iododesilylation ...