Enantioselective borohydride reduction catalyzed by optically active cobalt complexes

…, Y Ohtsuka, D Miyazaki, T Mukaiyama

Index: Yamada, Tohru; Nagata, Takushi; Sugi, Kiyoaki D.; Yorozu, Kiyotaka; Ikeno, Taketo; Ohtsuka, Yuhki; Miyazaki, Daichi; Mukaiyama, Teruaki Chemistry - A European Journal, 2003 , vol. 9, # 18 p. 4485 - 4509

Full Text: HTML

Citation Number: 81

Abstract

Abstract The highly enantioselective borohydride reduction of aromatic ketones or imines to the corresponding alcohols was developed in the presence of a catalytic amount of an optically active cobalt (II) complex catalyst. This enantioselective reduction is carried out using a precisely premodified borohydride with alcohols such as tetrahydrofurfuryl alcohol, ethanol and methanol. High optical yields are obtained by choosing the appropriate ...

Related Articles:

C-Alkylation and N-acylation of 4-amino-1-azabutadiene derivatives. A convenient route to monoalkylated 1, 3-diketones

[Barluenga, Jose; Jardon, Jesus; Gotor, Vicente Journal of Organic Chemistry, 1985 , vol. 50, # 6 p. 802 - 804]

High-yielding oxidation of β-hydroxyketones to β-diketones using o-iodoxybenzoic acid

[Bartlett, Samuel L.; Beaudry, Christopher M. Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9852 - 9855]

Reactivity of 1, 3-diimines. Reaction with heterocumulenes

[Barluenga, Jose; Rubio, Victor; Gotor, Vicente Journal of Organic Chemistry, 1980 , vol. 45, # 13 p. 2592 - 2596]

The regioselective preparation of 1, 3-diketones

[Wiles, Charlotte; Watts, Paul; Haswell, Stephen J.; Pombo-Villar, Esteban Tetrahedron Letters, 2002 , vol. 43, # 16 p. 2945 - 2948]

The regioselective preparation of 1, 3-diketones

[Wiles, Charlotte; Watts, Paul; Haswell, Stephen J.; Pombo-Villar, Esteban Tetrahedron Letters, 2002 , vol. 43, # 16 p. 2945 - 2948]

More Articles...