The Journal of antibiotics

Antibiotic activities and affinities for bacterial cell wall analogue of N-demethylvancomycin and its derivatives.

H Yan, D Qi, X Cheng, Z Song, W Li, B He

Index: Yan, Husheng; Qi, Dongfeng; Cheng, Xiaohui; Song, Zhengji; Li, Wenlan; He, Binglin Journal of Antibiotics, 1998 , vol. 51, # 8 p. 750 - 756

Full Text: HTML

Citation Number: 19

Abstract

N-Demethylvancomycin, which has been clinically used in China, is one member of vancomycin group (glycopeptide) antibiotics. It differs from vancomycin only in that methyl group on the amino group of the N-terminal residue of vancomycin has been replaced by H. By reductive alkylation of N-demethylvancomycin, we synthesized N-alkyl and N, N′-dialkyl N-demethylvancomycins, which closely correlated with vancomycin in structure. The ...

Related Articles:

Detailed binding sites of the antibiotics vancomycin and ristocetin A: determination of intermolecular distances in antibiotic/substrate complexes by use of the time- …

[Williams; Williamson; Butcher; Hammond Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1332 - 1339]

Detailed binding sites of the antibiotics vancomycin and ristocetin A: determination of intermolecular distances in antibiotic/substrate complexes by use of the time- …

[Williams; Williamson; Butcher; Hammond Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1332 - 1339]

Detailed binding sites of the antibiotics vancomycin and ristocetin A: determination of intermolecular distances in antibiotic/substrate complexes by use of the time- …

[Williams; Williamson; Butcher; Hammond Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1332 - 1339]

Enantioselective Solid??Phase Peptide Synthesis Using Traceless Chiral Coupling Reagents and Racemic Amino Acids

[Kolesinska, Beata; Kasperowicz-Frankowska, Katarzyna; Fraczyk, Justyna; Kaminski, Zbigniew J. Helvetica Chimica Acta, 2012 , vol. 95, # 11 p. 2084 - 2098]

More Articles...