Eugenol and its methyl ether in the synthesis of 3-methyl derivatives of 3, 4-dihydroisoquinoline

YV Shklyaev, AA Smolyak, AA Gorbunov

Index: Shklyaev, Yu. V.; Smolyak; Gorbunov Russian Journal of Organic Chemistry, 2011 , vol. 47, # 2 p. 239 - 244

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Citation Number: 5

Abstract

Abstract 3-Methyl derivatives of 1-substituted 3, 4-dihydroisoquinoline were obtained proceeding from eugenol and its methyl ether. The propylene oxide in a three-component reaction with veratrol and ethyl cycnoacetate provided the reaction products in a low yield. The isoeugenol in a linear synthesis also gives a low yield of the target compounds.

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