Journal of medicinal chemistry

Fluorinated analogs of leucine, methionine, and valine

J Lazar, WA Sheppard

Index: Journal of medicinal chemistry, , vol. 11, # 1 p. 138 - 140

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Citation Number: 12

Abstract

... 4,4,4-trifluoro-3-( trifluoromethy1)crotonic acids in 50 ml of 957, EtOH (1 g of 10% Pd-C ... 4,4,4-Trifluoro-3-( trifluoromethy1)butan-1-01 was obtained by the LiAlH4 reduction of 1 or the ... by keep- iiig a mixture of 80.0 g (0.37 mole) of 4, 140 g (0.74 mole) of p-toluenesulfonyl chloride ...

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