Purine N-Oxides. XIV. A Total Synthesis of a Pyrimidine N-Oxide, a Pteridine 1-N-Oxide, and Xanthine 3-N-Oxide1

RM Cresswell, HK Maurer, T Strauss…

Index: Cresswell,R.M. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 408 - 410

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Citation Number: 15

Abstract

The ring closure was accomplished by dissolving either the 6-amino-5-forn1amido-2, 4- dihydroxypyriini-dine 1-N-oxide (X) or the 5, g-dianiine V in hot formic acid and adding acetic anhydride. The xanthine 3-N-oxide (XI) obtained was slowly reduced to xanthine in the presence of very active Raney nickel but unreduced N-oxide was still present.