Tetrahedron letters

Solid-phase synthesis of 2-methoxyaniline derivatives by the traceless silicon linker strategy

S Curtet, M Langlois

Index: Curtet, Sophie; Langlois, Michel Tetrahedron Letters, 1999 , vol. 40, # 49 p. 8563 - 8566

Full Text: HTML

Citation Number: 16

Abstract

Application of the silicon linkage strategy to the solid-phase synthesis of the rich-electron o- anisidine derivatives is described. The protective t-Boc group was easily removed with B- catechol borane and the isocyanate was successfully prepared with the mild reagent (t-Boc) 2O DMAP. Carbamates, ureas or amides were prepared and released by cleavage with TFA at room temperature. This method can be used to prepare small focused libraries with ...

Related Articles:

Microwave-assisted synthesis of nano-sized cadmium oxide as a new and highly efficient catalyst for solvent free acylation of amines and alcohols

[Mazaheritehrani; Asghari; Orimi, R. Lotfi; Pahlavan Asian Journal of Chemistry, 2010 , vol. 22, # 4 p. 2554 - 2564]

Novel Periodic Mesoporous Silica Chlorides (PMSCl) with 2D P6mm Hexagonal Structures: Efficient Catalysts for the Beckmann Rearrangement

[Karimi, Babak; Behzadnia, Hesam Synlett, 2010 , # 13 p. 2019 - 2023]

Biosynthesis of antibiotic LL-C10037. alpha.: the steps beyond 3-hydroxyanthranilic acid

[Gould, Steven J.; Shen, Ben; Whittle, Yvonne G. Journal of the American Chemical Society, 1989 , vol. 111, # 20 p. 7932 - 7938]

Copper-catalyzed amidation of aryl iodides using KF/Al2O3: An improved protocol

[Hosseinzadeh, Rahman; Tajbakhsh, Mahmood; Mohadjerani, Maryam; Mehdinejad, Hamidreza Synlett, 2004 , # 9 p. 1517 - 1520]

A novel and simple transamidation of carboxamides in 1, 4-dioxane without a catalyst

[Vanjari, Rajeshwer; Allam, Bharat Kumar; Singh, Krishna Nand Tetrahedron Letters, 2013 , vol. 54, # 20 p. 2553 - 2555]

More Articles...