Asymmetric Synthesis of SM-9164, a Biologically Active Enantiomer of Antifungal Agent SM-8668.

H Miyauchi, T Nakamura, N Ohashi

Index: Bulletin of the Chemical Society of Japan, , vol. 69, # 9 p. 2625 - 2632

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Citation Number: 10

Abstract

... 100 mg, 0.58 mmol) and dihydropyran (DHP, 80 ul, 0.87 mmol) in dichloromethane (2.0 ml) at 0 °C was added pyridinium p—toluenesulfonate (PPTS ... Jpn, 69, N0 ... 9 (1996) 2629 J=6.9 Hz, CH), 672—691 (2H, m), and 7.22 (lH, m). Wittig Reaction of Ketone 12h [Entry 21:1” Ketone ...

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