The conformational analysis of saturated heterocycles. Part XXIII. Hexahydropyrimidines

RAY Jones, AR Katritzky, M Snarey

Index: Jones,R.A.Y. et al. Journal of the Chemical Society [Section] B: Physical Organic, 1970 , p. 131 - 135

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Citation Number: 28

Abstract

The preparations of some N-substituted hexahydropyrimidines are described. Their electric dipole moments have been measured in cyclohexane solution and interpreted in terms of their conformations. The conformational free-energy differences between axial and equatorial N-methyl and N-ethyl groups are a little smaller than in the corresponding N- alkylpiperidines and accord with a repulsion between two axial lone electron pairs of ...