Fast Racemisation of Chiral Amines and Alcohols by Using Cationic Half??Sandwich Ruthena??and Iridacycle Catalysts

T Jerphagnon, AJA Gayet, F Berthiol…

Index: Jerphagnon, Thomas; Gayet, Arnaud J.A.; Berthiol, Florian; Ritleng, Vincent; Mrsic, Natasa; Meetsma, Auke; Pfeffer, Michel; Minnaard, Adriaan J.; Feringa, Ben L.; De Vries, Johannes G. Chemistry - A European Journal, 2009 , vol. 15, # 46 p. 12780 - 12790

Full Text: HTML

Citation Number: 42

Abstract

Abstract The lipase-catalysed resolution of alcohols and amines yields only 50% of the desired enantiopure product. However, addition of a racemisation catalyst leads to 100% yield in what is called a dynamic kinetic resolution (DKR). There is a need for new racemisation catalysts that are fast and compatible with the conditions of the enzymatic reaction. We show that cationic half-sandwich ruthena-and iridacycle complexes are ...

Related Articles:

Ruthenium (II) complex catalysts bearing a pyridyl-supported pyrazolyl-imine ligand for transfer hydrogenation of ketones

[Zhao, Miao; Yu, Zhengkun; Yan, Shenggang; Li, Yang Journal of Organometallic Chemistry, 2009 , vol. 694, # 19 p. 3068 - 3075]

Regioselective hydroboration-oxidation and-amination of fluoro-substituted styrenes

[Ramachandran, P. Veeraraghavan; Madhi, Sateesh; O'Donnell, Martin J. Journal of Fluorine Chemistry, 2006 , vol. 127, # 9 p. 1252 - 1255]

Cerium (III) bromate as a new reagent in oxidation of organic compounds

[Shaabani, Ahmad; Lee, Donald G. Synthetic Communications, 2003 , vol. 33, # 11 p. 1845 - 1854]

QUANTUM CHEMISTRY AND COMPUTATION CHEMISTRY

[Li, Jia; Wang, Chao; Xue, Dong; Wei, Yawen; Xiao, Jianliang Green Chemistry, 2013 , vol. 15, # 10 p. 2685 - 2689]

Photohydration of styrenes and phenylacetylenes. General acid catalysis and Broensted relationships

[McEwen, John; Yates, Keith Journal of the American Chemical Society, 1987 , vol. 109, # 19 p. 5800 - 5808]

More Articles...